It is one of several Spider-Man related spinoffs in Sony’s pipeline, including “Kraven the Hunter,” featuring Aaron Taylor-Johnson and Ariana DeBose. “Madame Web” is Sony’s first modern comic book adaptation to feature a woman in the headlining role. Clarkson, a Marvel alum through “Jessica Jones” and “The Defenders,” is directing “Madame Web.” Matt Sazama and Burk Sharpless, the duo behind Jared Leto’s vampire antihero “Morbius,” are writing the screenplay. Given her condition, though, she’s never battled villains herself.

Her supernatural abilities prove to be greatly beneficial to Spider-Man and his fellow arachnid allies, like Spider-Woman. In the Marvel comics, Madame Web is a paralyzed, elderly woman with myasthenia gravis, a chronic autoimmune disorder requiring her to connect to a life support system resembling a spider web. The movie will serve as an origin story for Madame Web, a clairvoyant whose psychic abilities allow her to see within the spider world itself. They will appear in the comic-book adventure alongside Dakota Johnson, who is playing the title character, as well as Sydney Sweeney of “Euphoria” fame. “Ghostbusters: Afterlife” actor Celeste O’Connor has been cast in “ Madame Web,” an upcoming installment in Sony’s Universe of Marvel Characters.

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